SMIM43

Across TCGA patient cohorts, SMIM43 protein abundance is significantly associated with the RNA expression of many other genes, with 195 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMIM43-associated genes across cancer lineages are JOSD1, FBXO7, and DHDH. Each is linked with SMIM43 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM43-to-partner and partner-to-SMIM43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM43 versus JOSD1 in GBM, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM43→partner) and Y-score (partner→SMIM43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	JOSD1 →	+0.396	+0.863	.007	.008	3	1
GBM	FBXO7 →	+0.479	+0.636	.007	.007	3	1
GBM	DHDH →	+0.876	+0.863	.008	.008	3	1
GBM	ZNRF4 →	+0.086	+0.681	.001	.005	3	1
GBM	DNPH1 →	-1.000	-0.863	<.001	.008	3	1
GBM	NPR3 →	+0.406	+0.863	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 195 associations by consensus.

SMIM43 vs JOSD1 — GBM

Explore this scatter interactively →