SMIM34B

Across TCGA cell cohorts, SMIM34B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,230 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SMIM34B-associated GO terms across cancer lineages are Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Protein exit from endoplasmic reticulum, and Cilium movement. Each is linked with SMIM34B in more than 6 cancer types. Because this analysis shows association rather than direction, both SMIM34B-to-partner and partner-to-SMIM34B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by SMIM34B-low versus SMIM34B-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM34B→partner) and Y-score (partner→SMIM34B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.078	-0.101	.003	.007	3	7
BONE	Protein exit from endoplasmic reticulum →	+0.083	+0.202	.005	.009	3	7
LUNG_SCLC	Cilium movement →	-0.044	-1.211	<.001	.005	3	6
BLOOD_Lymphoma	Negative regulation of apoptotic signaling pathway →	+0.062	+0.382	<.001	.008	3	6
OVARY	Endoplasmic reticulum unfolded protein response →	+0.073	+0.147	.002	<.001	3	6
CNS	Regulation of myoblast fusion →	+0.076	+0.168	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,230 associations by consensus.

Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by SMIM34B expression — OVARY

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