SMIM33

Across TCGA patient cohorts, SMIM33 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,917 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SMIM33-associated proteins across cancer lineages are RTN1_S352, IL16_S845, and IQGAP2_S16. Each is linked with SMIM33 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMIM33-to-partner and partner-to-SMIM33 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM33 versus RTN1_S352 in CCRCC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM33→partner) and Y-score (partner→SMIM33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RTN1_S352 →	+0.834	+0.262	<.001	<.001	3	5
GBM	IL16_S845 →	+0.997	+0.099	<.001	<.001	3	5
LUAD	IQGAP2_S16 →	+1.017	+0.286	<.001	<.001	3	5
LSCC	GAB3_S371 →	+1.010	+0.215	<.001	<.001	3	5
GBM	RGS10 →	+0.452	+0.129	.004	.002	3	4
CCRCC	RHBDF2_S328 →	+0.690	+0.229	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,917 associations by consensus.

SMIM33 vs RTN1_S352 — CCRCC

Explore this scatter interactively →