SMIM33

Across TCGA cell cohorts, SMIM33 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,730 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SMIM33-associated GO terms across cancer lineages are Reticulophagy, Humoral immune response, and Activation of GTPase activity. Each is linked with SMIM33 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMIM33-to-partner and partner-to-SMIM33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Reticulophagy grouped by SMIM33-low versus SMIM33-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM33→partner) and Y-score (partner→SMIM33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Reticulophagy →	+0.048	+0.014	.003	.009	3	5
SOFT_TISSUE	Humoral immune response →	-0.099	-0.002	.003	.003	3	4
SOFT_TISSUE	Activation of GTPase activity →	+0.056	+0.003	.004	.008	3	4
SOFT_TISSUE	Neurotransmitter loading into synaptic vesicle →	-0.855	-0.003	.006	.008	3	4
BREAST	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.141	+0.067	.002	.006	3	4
BLOOD_Lymphoma	Neurotransmitter receptor diffusion trapping →	-0.782	-0.016	.002	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,730 associations by consensus.

Reticulophagy by SMIM33 expression — KIDNEY

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