SMIM32

Across TCGA patient cohorts, SMIM32 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,700 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SMIM32-associated proteins across cancer lineages are PHRF1_S814, PLEKHA6, and SOX6_S454. Each is linked with SMIM32 in more than 3 cancer types. Because this analysis shows association rather than direction, both SMIM32-to-partner and partner-to-SMIM32 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM32 versus PHRF1_S814 in LSCC, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM32→partner) and Y-score (partner→SMIM32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PHRF1_S814 →	-0.451	-0.416	<.001	<.001	3	4
PDAC	PLEKHA6 →	+0.481	+1.094	<.001	<.001	3	3
CCRCC	SOX6_S454 →	+0.615	+1.571	<.001	<.001	3	3
CCRCC	EIPR1 →	+0.203	+1.525	<.001	.001	3	3
LSCC	CAMSAP3 →	+0.602	+0.502	<.001	<.001	3	3
BRCA	FLNA_S1459 →	-0.517	-0.312	<.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,700 associations by consensus.

SMIM32 vs PHRF1_S814 — LSCC

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