SMIM31

Across TCGA cell cohorts, SMIM31 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,938 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SMIM31-associated GO terms across cancer lineages are Microtubule depolymerization, Acetylcholine biosynthetic process, and Luteinization. Each is linked with SMIM31 in more than 5 cancer types. Because this analysis shows association rather than direction, both SMIM31-to-partner and partner-to-SMIM31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule depolymerization grouped by SMIM31-low versus SMIM31-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM31→partner) and Y-score (partner→SMIM31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule depolymerization →	-0.075	-1.183	<.001	<.001	3	6
STOMACH	Acetylcholine biosynthetic process →	+1.902	+2.214	<.001	.001	3	5
STOMACH	Luteinization →	-1.178	-1.287	<.001	.002	3	5
STOMACH	Regulation of single-species biofilm formation →	+1.502	+2.039	<.001	.004	3	5
STOMACH	Negative regulation of single-species biofilm formation →	+1.502	+2.039	<.001	.004	3	5
STOMACH	Regulation of single-species biofilm formation in or on host organism →	+1.502	+2.039	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,938 associations by consensus.

Microtubule depolymerization by SMIM31 expression — LARGE_INTESTINE

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