SMIM30

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMIM30 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMIM30-associated genes across cancer lineages are RNU6-1123P, RNU6-1082P, and RNA5SP508. Each is linked with SMIM30 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM30-to-partner and partner-to-SMIM30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM30→partner) and Y-score (partner→SMIM30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-1123P →+0.612+5.551<.001.00431
UCECRNU6-1082P →+0.568+5.551<.001.00431
UCECRNA5SP508 →+0.751+5.694<.001.00331
UCECELOBP3 →+0.389+5.420<.001.00531
UCECZNF519P4 →+0.846+5.299<.001.00631
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

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