SMIM3

Across TCGA patient cohorts, SMIM3 RNA expression is significantly associated with the RNA expression of many other genes, with 17,690 significant associations in total. UVM shows the largest number of these associations.

The most reproducible SMIM3-associated genes across cancer lineages are LOX, CRISPLD2, and SERPINE1. Each is linked with SMIM3 in more than 30 cancer types. Because this analysis shows association rather than direction, both SMIM3-to-partner and partner-to-SMIM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM3 versus LOX in TGCT, with a Pearson correlation of 0.70.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM3→partner) and Y-score (partner→SMIM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	LOX →	+2.295	+1.148	<.001	<.001	3	31
CHOL	CRISPLD2 →	+1.609	+1.315	<.001	.003	3	30
CHOL	SERPINE1 →	+3.213	+1.715	<.001	<.001	3	30
THCA	FN1 →	+3.106	+0.740	<.001	<.001	3	30
GBM	MMP19 →	+1.604	+1.100	<.001	<.001	3	30
BLCA	GLIPR1 →	+1.391	+1.386	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,690 associations by consensus.

SMIM3 vs LOX — TGCT

Explore this scatter interactively →