Across TCGA pan-cancer cohorts, SMIM29 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SMIM29 data layer compared with 26 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher SMIM29 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SMIM29 expression acts as an unfavorable survival marker.

CESC and UCEC are the cancer types where SMIM29 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	II,III,IV	0.053	0.786	<.001	42	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SMIM29 tumor-vs-normal RNA expression · all SMIM29 data types