SMIM29

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMIM29 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMIM29-associated genes across cancer lineages are RNA5SP517, RNA5SP262, and MIR3675. Each is linked with SMIM29 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM29-to-partner and partner-to-SMIM29 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM29→partner) and Y-score (partner→SMIM29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNA5SP517 →+0.238+7.640<.001.00932
BRCARNA5SP262 →+0.314+8.055.001.00731
BRCAMIR3675 →+0.418+8.471<.001.00531
UCECRNVU1-28 →+1.178+3.442<.001.00131
BRCARNA5SP374 →+0.322+8.055<.001.00731
BRCAMIR1237 →+0.377+7.731<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

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