SMIM27

Across TCGA patient cohorts, SMIM27 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,077 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SMIM27-associated proteins across cancer lineages are APTX, SMU1, and DNAJA1. Each is linked with SMIM27 in more than 5 cancer types. Because this analysis shows association rather than direction, both SMIM27-to-partner and partner-to-SMIM27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM27 versus APTX in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM27→partner) and Y-score (partner→SMIM27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	APTX →	+0.367	+0.350	<.001	<.001	3	6
HNSC	SMU1 →	+0.197	+0.462	<.001	.001	3	6
LSCC	DNAJA1 →	+0.279	+0.375	<.001	<.001	3	5
HNSC	BAG1 →	+0.375	+0.582	<.001	.001	3	5
GBM	CHMP5 →	+0.250	+0.374	<.001	<.001	3	4
HNSC	PSIP1_S106 →	+0.520	+0.484	<.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,077 associations by consensus.

SMIM27 vs APTX — LSCC

Explore this scatter interactively →