Across TCGA cell cohorts, SMIM23 RNA expression is significantly associated with the mutation status of many other genes, with 321 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMIM23-associated genes across cancer lineages are ACAN, AKAP11, and PARP14. Each is linked with SMIM23 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM23-to-partner and partner-to-SMIM23 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM23→partner) and Y-score (partner→SMIM23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	ACAN →	+3.285	+0.024	.009	<.001	3	2
URINARY_TRACT	AKAP11 →	+5.087	+0.013	.004	<.001	3	2
OESOPHAGUS	PARP14 →	+4.906	+0.023	.006	<.001	3	2
BLOOD_Leukemia	ABCC1 →	+4.247	+0.012	.004	<.001	3	2
BLOOD_Leukemia	NEK9 →	+4.569	+0.015	.003	<.001	3	2
BLOOD_Leukemia	ORC3 →	+4.984	+0.018	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 321 associations by consensus.

Exploration

SMIM23 survival (RNA) · tumor vs normal (RNA) · all SMIM23 data types