SMIM22

Across TCGA patient cohorts, SMIM22 RNA expression is significantly associated with the RNA expression of many other genes, with 14,032 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible SMIM22-associated genes across cancer lineages are ROGDI, ELMO3, and TMEM125. Each is linked with SMIM22 in more than 25 cancer types. Because this analysis shows association rather than direction, both SMIM22-to-partner and partner-to-SMIM22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM22 versus ROGDI in LAML, with a Pearson correlation of 0.68.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM22→partner) and Y-score (partner→SMIM22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	ROGDI →	+1.471	+0.776	<.001	<.001	3	26
UCS	ELMO3 →	+2.160	+3.028	<.001	<.001	3	25
UCS	TMEM125 →	+2.490	+2.966	<.001	<.001	3	25
UCS	KRTCAP3 →	+1.976	+2.229	<.001	<.001	3	25
UCS	BICDL2 →	+2.382	+2.772	<.001	<.001	3	25
UCS	RAB25 →	+3.882	+2.753	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,032 associations by consensus.

SMIM22 vs ROGDI — LAML

Explore this scatter interactively →