SMIM22

Across TCGA patient cohorts, SMIM22 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,291 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SMIM22-associated proteins across cancer lineages are SLC44A4, CIB1, and SELENBP1. Each is linked with SMIM22 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMIM22-to-partner and partner-to-SMIM22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM22 versus SLC44A4 in LUAD, with a Pearson correlation of 0.77.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM22→partner) and Y-score (partner→SMIM22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SLC44A4 →	+1.190	+0.641	<.001	<.001	3	5
BRCA	CIB1 →	+0.666	+0.591	<.001	<.001	3	4
COAD	SELENBP1 →	+0.715	+0.289	<.001	<.001	3	4
COAD	PBLD →	+0.587	+0.480	<.001	<.001	3	3
LUAD	PLEKHA6 →	+0.533	+0.431	<.001	<.001	3	3
PDAC	RAB17 →	+0.910	+0.546	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,291 associations by consensus.

SMIM22 vs SLC44A4 — LUAD

Explore this scatter interactively →