SMIM19

Across TCGA patient cohorts, SMIM19 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,451 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SMIM19-associated proteins across cancer lineages are POLB, ERLIN2, and VDAC3. Each is linked with SMIM19 in more than 6 cancer types. Because this analysis shows association rather than direction, both SMIM19-to-partner and partner-to-SMIM19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM19 versus POLB in LSCC, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM19→partner) and Y-score (partner→SMIM19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	POLB →	+0.509	+0.664	<.001	<.001	3	7
BRCA	ERLIN2 →	+0.851	+0.913	<.001	<.001	3	6
BRCA	VDAC3 →	+0.666	+0.696	<.001	<.001	3	5
HNSC	SEC24A →	-0.258	-0.674	<.001	<.001	3	5
BRCA	STK17B →	-0.299	-0.357	<.001	.002	3	5
UCEC	BIN2 →	-0.595	-0.584	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,451 associations by consensus.

SMIM19 vs POLB — LSCC

Explore this scatter interactively →