SMIM19

Across TCGA patient cohorts, SMIM19 protein abundance is significantly associated with the RNA expression of many other genes, with 2,639 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMIM19-associated genes across cancer lineages are RNF170, SYT16, and KIF5C. Each is linked with SMIM19 in more than 2 cancer types. Because this analysis shows association rather than direction, both SMIM19-to-partner and partner-to-SMIM19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM19 versus RNF170 in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM19→partner) and Y-score (partner→SMIM19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNF170 →	+0.630	+0.367	<.001	.004	3	3
GBM	SYT16 →	-1.227	-0.397	.002	.002	3	2
GBM	KIF5C →	-1.157	-0.452	<.001	<.001	3	2
OV	TAPBPL →	+1.139	+0.493	<.001	<.001	3	2
OV	ZDHHC5 →	+0.607	+0.711	<.001	<.001	3	2
OV	CD200 →	-1.012	-0.350	.008	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,639 associations by consensus.

SMIM19 vs RNF170 — BRCA

Explore this scatter interactively →