SMIM19

Across TCGA cell cohorts, SMIM19 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,981 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SMIM19-associated GO terms across cancer lineages are Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Vesicle coating, and tRNA export from nucleus. Each is linked with SMIM19 in more than 11 cancer types. Because this analysis shows association rather than direction, both SMIM19-to-partner and partner-to-SMIM19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by SMIM19-low versus SMIM19-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM19→partner) and Y-score (partner→SMIM19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.107	-0.869	.006	.008	3	12
LUNG_SCLC	Vesicle coating →	+0.089	+0.662	<.001	.002	3	12
BLOOD_Myeloma	tRNA export from nucleus →	-0.139	-1.233	<.001	<.001	3	10
OVARY	Pyrimidine nucleoside diphosphate biosynthetic process →	-0.120	-0.970	<.001	<.001	3	10
PANCREAS	Maturation of SSU-rRNA →	-0.094	-1.281	.001	<.001	3	9
BLOOD_Myeloma	Transcription initiation at RNA polymerase I promoter →	-0.091	-0.809	.002	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,981 associations by consensus.

Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by SMIM19 expression — OESOPHAGUS

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