SMIM17

Across TCGA cell cohorts, SMIM17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,093 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMIM17-associated GO terms across cancer lineages are Microtubule anchoring at microtubule organizing center, COP9 signalosome assembly, and Positive regulation of double-strand break repair. Each is linked with SMIM17 in more than 8 cancer types. Because this analysis shows association rather than direction, both SMIM17-to-partner and partner-to-SMIM17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule anchoring at microtubule organizing center grouped by SMIM17-low versus SMIM17-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM17→partner) and Y-score (partner→SMIM17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Microtubule anchoring at microtubule organizing center →	+0.076	+0.225	<.001	<.001	3	9
LIVER	COP9 signalosome assembly →	+0.134	+0.255	.005	.004	3	8
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.072	+0.376	.001	.001	3	8
SOFT_TISSUE	Bile acid signaling pathway →	+0.179	+0.328	<.001	.003	3	8
LUNG_SCLC	Regulation of RNA splicing →	+0.080	+0.993	<.001	<.001	3	8
BLOOD_Leukemia	Regulation of alternative mRNA splicing, via spliceosome →	+0.087	+0.332	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,093 associations by consensus.

Microtubule anchoring at microtubule organizing center by SMIM17 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →