Across TCGA cell cohorts, SMIM15 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,925 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SMIM15-associated GO terms across cancer lineages are CAAX-box protein maturation, Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage, and Regulation of protection from non-homologous end joining at telomere. Each is linked with SMIM15 in more than 10 cancer types. Because this analysis shows association rather than direction, both SMIM15-to-partner and partner-to-SMIM15 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM15→partner) and Y-score (partner→SMIM15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CAAX-box protein maturation →	+0.114	+0.405	<.001	.005	2	11
LUNG_NSCLC_LUSC	Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage →	-0.066	-0.541	.001	.008	3	8
STOMACH	Regulation of protection from non-homologous end joining at telomere →	-0.155	-0.916	<.001	.001	3	8
STOMACH	Negative regulation of protection from non-homologous end joining at telomere →	-0.155	-0.916	<.001	.001	3	8
STOMACH	Telomeric DNA-containing double minutes formation →	-0.155	-0.916	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mRNA 3'-end processing →	+0.070	+0.468	.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,925 associations by consensus.

Exploration

SMIM15 survival (RNA) · tumor vs normal (RNA) · all SMIM15 data types