SMIM12

Across TCGA patient cohorts, SMIM12 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,333 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SMIM12-associated proteins across cancer lineages are KHDRBS1, ZCCHC17, and ZMYM4. Each is linked with SMIM12 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMIM12-to-partner and partner-to-SMIM12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM12 versus KHDRBS1 in LSCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM12→partner) and Y-score (partner→SMIM12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KHDRBS1 →	+0.227	+0.289	.001	<.001	3	5
BRCA	ZCCHC17 →	+0.396	+0.420	<.001	<.001	3	4
OV	ZMYM4 →	+0.330	+0.529	.001	.001	3	4
OV	TXLNA →	+0.264	+0.305	<.001	.002	3	4
LSCC	PHC2 →	+0.313	+0.251	.007	.005	3	4
LSCC	SPCS3 →	-0.577	-0.318	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,333 associations by consensus.

SMIM12 vs KHDRBS1 — LSCC

Explore this scatter interactively →