SMIM12

Across TCGA cell cohorts, SMIM12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,576 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SMIM12-associated GO terms across cancer lineages are RISC complex assembly, Mitotic spindle elongation, and Mitotic spindle midzone assembly. Each is linked with SMIM12 in more than 15 cancer types. Because this analysis shows association rather than direction, both SMIM12-to-partner and partner-to-SMIM12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RISC complex assembly grouped by SMIM12-low versus SMIM12-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM12→partner) and Y-score (partner→SMIM12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	RISC complex assembly →	+0.116	+0.962	.001	.003	3	16
PANCREAS	Mitotic spindle elongation →	+0.278	+0.973	<.001	<.001	3	14
PANCREAS	Mitotic spindle midzone assembly →	+0.278	+0.973	<.001	<.001	3	14
BREAST	Positive regulation of mitotic cell cycle phase transition →	+0.109	+0.958	<.001	.002	3	11
URINARY_TRACT	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.132	+0.964	.003	<.001	3	11
SKIN	Pyrimidine nucleoside monophosphate biosynthetic process →	+0.104	+0.487	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,576 associations by consensus.

RISC complex assembly by SMIM12 expression — BREAST

Explore this box plot interactively →