Across TCGA pan-cancer cohorts, SMIM11P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SMIM11P1’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where SMIM11P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SMIM11P1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

ESCA and THCA are the cancer types where SMIM11P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SMIM11P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	+0.295	.022	2	view →
THCA	All	All	−0.055	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SMIM11P1 RNA expression & survival · all SMIM11P1 data types