Across TCGA patient cohorts, SMIM10L2B mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMIM10L2B-associated genes across cancer lineages are ZNF519P4, DEFB104A, and GTSE1. Each is linked with SMIM10L2B in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM10L2B-to-partner and partner-to-SMIM10L2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM10L2B→partner) and Y-score (partner→SMIM10L2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF519P4 →	+0.288	+3.077	<.001	.009	3	2
UCEC	DEFB104A →	+0.134	+4.736	<.001	.003	3	1
UCEC	GTSE1 →	+0.846	+3.234	.008	.009	3	1
UCEC	TNPO1 →	+0.829	+3.191	.001	.009	3	1
UCEC	RNU6-6P →	+0.628	+3.227	<.001	.001	3	1
UCEC	MIR7702 →	+0.373	+5.060	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

Exploration

SMIM10L2B survival (RNA) · tumor vs normal (RNA) · all SMIM10L2B data types