SMIM10L2B

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMIM10L2B mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMIM10L2B-associated genes across cancer lineages are Myocytes, mv Endothelial cells, and NKT. Each is linked with SMIM10L2B in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM10L2B-to-partner and partner-to-SMIM10L2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM10L2B→partner) and Y-score (partner→SMIM10L2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMyocytes →+0.063+3.212<.001.01021
UCECmv Endothelial cells →-0.035-3.159.007.02011
UCECNKT →-0.163-3.169.005.02011
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration