SMIM10L2B-AS1

Across TCGA pan-cancer cohorts, SMIM10L2B-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated SMIM10L2B-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher SMIM10L2B-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SMIM10L2B-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and UCEC show a favorable association.

UCS, STAD, and LGG are the cancer types where SMIM10L2B-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	II,III,IV	0.634	0.241	<.001	64	view →
STAD	OS	Tertile	III,IV	0.464	0.667	.011	36	view →
LGG	OS	Median	All	0.353	0.509	<.001	34	view →
KIRP	DFS	Tertile	II,III,IV	0.436	0.754	.012	31	view →
READ	OS	Tertile	IV	0.289	0.899	<.001	27	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
PCPG	OS	Tertile	All	0.939	1.000	.034	10	view →
PRAD	OS	Tertile	All	0.747	0.985	.012	8	view →
CESC	DFS	Quartile	IV	0.210	0.541	.040	6	view →
THCA	DFS	Tertile	IV	0.500	0.947	.002	6	view →
UCEC	OS	Median	All	0.706	0.658	.035	6	view →
DLBC	DFS	Tertile	All	1.000	0.665	.036	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

SMIM10L2B-AS1–UCS (DFS)

Open the UCS breakdown →