SMIM1

Across TCGA cell cohorts, SMIM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,153 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMIM1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of phospholipid efflux, and Positive regulation of phospholipid efflux. Each is linked with SMIM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SMIM1-to-partner and partner-to-SMIM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by SMIM1-low versus SMIM1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM1→partner) and Y-score (partner→SMIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.104	+1.638	<.001	.002	3	10
SKIN	Regulation of phospholipid efflux →	+1.176	+1.246	<.001	<.001	3	10
SKIN	Positive regulation of phospholipid efflux →	+1.176	+1.246	<.001	<.001	3	10
PANCREAS	Sterol transport →	+0.063	+0.984	.007	.004	3	10
OVARY	Regulation of low-density lipoprotein particle receptor catabolic process →	+0.175	+1.475	<.001	<.001	2	10
BONE	Establishment of epithelial cell apical/basal polarity →	-0.173	-0.904	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,153 associations by consensus.

Regulation of myoblast fusion by SMIM1 expression — OVARY

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