SMG7

Across TCGA patient cohorts, SMG7 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,467 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMG7-associated proteins across cancer lineages are RBBP5, RPRD2, and ADAR. Each is linked with SMG7 in more than 6 cancer types. Because this analysis shows association rather than direction, both SMG7-to-partner and partner-to-SMG7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMG7 versus RBBP5 in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMG7→partner) and Y-score (partner→SMG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RBBP5 →	+0.286	+0.932	<.001	<.001	3	7
UCEC	RPRD2 →	+0.301	+0.569	<.001	<.001	3	7
UCEC	ADAR →	+0.270	+0.525	<.001	<.001	3	7
HNSC	C1orf35 →	+0.466	+1.011	<.001	<.001	3	7
GBM	CDC73 →	+0.307	+0.472	<.001	<.001	3	7
LSCC	SF3B1 →	+0.282	+0.709	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,467 associations by consensus.

SMG7 vs RBBP5 — HNSC

Explore this scatter interactively →