Across TCGA pan-cancer cohorts, SMG1P4 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated SMG1P4 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher SMG1P4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SMG1P4 expression acts as an unfavorable survival marker.

BRCA are the cancer types where SMG1P4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	III,IV	0.114	0.544	.035	8	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: SMG1P4 tumor-vs-normal RNA expression · all SMG1P4 data types