Across TCGA patient cohorts, SMG1P4 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMG1P4-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tem, and CLP. Each is linked with SMG1P4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMG1P4-to-partner and partner-to-SMG1P4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMG1P4→partner) and Y-score (partner→SMG1P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.019	+2.430	.002	.029	3	1
UCEC	CD8+ Tem →	+0.004	+4.744	<.001	.040	3	1
UCEC	CLP →	-0.067	-3.000	.042	.036	3	1
UCEC	HSC →	+0.141	+2.180	.014	.036	3	1
UCEC	Macrophages M2 →	+0.015	+2.287	.005	.030	3	1
UCEC	CD4+ naive T-cells →	+0.011	+3.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

SMG1P4 survival (RNA) · tumor vs normal (RNA) · all SMG1P4 data types