SMG1P3

Across TCGA patient cohorts, SMG1P3 mutation is significantly associated with the RNA expression of many other genes, with 81 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMG1P3-associated genes across cancer lineages are RNA5SP414, MIR7702, and WHAMM. Each is linked with SMG1P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMG1P3-to-partner and partner-to-SMG1P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP414 grouped by SMG1P3-low versus SMG1P3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMG1P3→partner) and Y-score (partner→SMG1P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP414 →	+0.812	+2.670	<.001	.009	3	1
UCEC	MIR7702 →	+0.373	+5.060	<.001	.001	3	1
UCEC	WHAMM →	+0.574	+3.234	<.001	.009	3	1
UCEC	SEC13 →	+0.571	+3.210	.001	.009	3	1
UCEC	HINT1 →	+0.695	+3.213	.002	.009	3	1
UCEC	NUDCD2 →	+0.624	+3.201	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

RNA5SP414 by SMG1P3 expression — UCEC

Explore this box plot interactively →