SMDT1

Across TCGA patient cohorts, SMDT1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,455 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SMDT1-associated genes across cancer lineages are MCU, CKAP2, and ZBTB2. Each is linked with SMDT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SMDT1-to-partner and partner-to-SMDT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMDT1 versus MCU in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMDT1→partner) and Y-score (partner→SMDT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MCU →	+0.523	+0.608	.007	.003	3	4
OV	CKAP2 →	-0.779	-0.408	<.001	<.001	3	3
BRCA	ZBTB2 →	-0.452	-0.320	.008	.006	2	4
GBM	ZNF530 →	-0.754	-1.130	.002	.003	3	3
GBM	YPEL4 →	-0.445	-1.115	.002	.001	3	3
GBM	BRSK2 →	-1.480	-0.648	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,455 associations by consensus.

SMDT1 vs MCU — UCEC

Explore this scatter interactively →