SMDT1

Across TCGA cell cohorts, SMDT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,048 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SMDT1-associated GO terms across cancer lineages are L-glutamine catabolic process, Pyruvate import into mitochondria, and Transcription initiation at RNA polymerase I promoter. Each is linked with SMDT1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SMDT1-to-partner and partner-to-SMDT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-glutamine catabolic process grouped by SMDT1-low versus SMDT1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMDT1→partner) and Y-score (partner→SMDT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	L-glutamine catabolic process →	-0.202	-0.822	<.001	.001	2	10
SOFT_TISSUE	Pyruvate import into mitochondria →	+0.143	+0.444	<.001	.004	3	9
BREAST	Transcription initiation at RNA polymerase I promoter →	-0.117	-0.963	<.001	.001	3	8
KIDNEY	Symbiont-mediated disruption of host cellular anatomical structure →	+0.119	+0.896	.009	.003	3	7
KIDNEY	Symbiont-mediated disruption of host anatomical structure →	+0.119	+0.896	.009	.003	3	7
LIVER	Negative regulation of actin nucleation →	+0.279	+0.753	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,048 associations by consensus.

L-glutamine catabolic process by SMDT1 expression — BREAST

Explore this box plot interactively →