Across TCGA patient cohorts, SMCR5 RNA expression is significantly associated with the RNA expression of many other genes, with 18,345 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible SMCR5-associated genes across cancer lineages are XPC-AS1, CTBP1-AS, and NKTR. Each is linked with SMCR5 in more than 28 cancer types. Because this analysis shows association rather than direction, both SMCR5-to-partner and partner-to-SMCR5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMCR5→partner) and Y-score (partner→SMCR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	XPC-AS1 →	+0.608	+0.058	<.001	<.001	3	29
UVM	CTBP1-AS →	+0.726	+0.042	<.001	<.001	3	29
THYM	NKTR →	+1.022	+0.105	<.001	<.001	3	29
LAML	ZNRD1ASP →	+0.599	+0.653	<.001	<.001	3	29
UVM	RAD51-AS1 →	+1.123	+0.050	<.001	<.001	3	28
KIRC	RPL23AP64 →	+1.048	+0.090	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,345 associations by consensus.

Exploration

SMCR5 survival (RNA) · tumor vs normal (RNA) · all SMCR5 data types