Across TCGA patient cohorts, SMCR5 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,218 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMCR5-associated proteins across cancer lineages are RBMX, XRN2, and CSNK1A1_T321. Each is linked with SMCR5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SMCR5-to-partner and partner-to-SMCR5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMCR5→partner) and Y-score (partner→SMCR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBMX →	+0.452	+0.540	<.001	<.001	3	3
GBM	XRN2 →	+0.252	+0.412	<.001	.001	3	3
HNSC	CSNK1A1_T321 →	-0.564	-0.629	<.001	.009	3	3
GBM	STRBP →	+0.475	+0.522	<.001	<.001	3	3
BRCA	TAF6_S626 →	+0.707	+0.076	<.001	.007	3	3
LSCC	ALKBH5 →	+0.359	+0.384	.004	.001	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,218 associations by consensus.

Exploration

SMCR5 survival (RNA) · tumor vs normal (RNA) · all SMCR5 data types