Across TCGA patient cohorts, SMCR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,134 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SMCR2-associated GO terms across cancer lineages are rRNA base methylation, Mitotic intra-S DNA damage checkpoint signaling, and Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Each is linked with SMCR2 in more than 21 cancer types. Because this analysis shows association rather than direction, both SMCR2-to-partner and partner-to-SMCR2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMCR2→partner) and Y-score (partner→SMCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	rRNA base methylation →	+0.051	+1.044	<.001	.002	3	22
ESCA	Mitotic intra-S DNA damage checkpoint signaling →	+0.041	+0.197	.009	<.001	2	20
STAD	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.038	+0.069	<.001	.008	2	19
THYM	Depyrimidination →	+0.046	+0.502	<.001	<.001	3	18
STAD	NADH dehydrogenase complex assembly →	+0.036	+0.078	<.001	<.001	3	17
THYM	Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' →	+0.041	+0.659	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,134 associations by consensus.

Exploration

SMCR2 survival (RNA) · tumor vs normal (RNA) · all SMCR2 data types