SMCO3

Across TCGA patient cohorts, SMCO3 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,434 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMCO3-associated proteins across cancer lineages are APCS, NDE1_S282, and RASA3_S809. Each is linked with SMCO3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SMCO3-to-partner and partner-to-SMCO3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMCO3 versus APCS in UCEC, with a Pearson correlation of 0.71.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMCO3→partner) and Y-score (partner→SMCO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	APCS →	+1.443	+1.031	<.001	.001	3	4
BRCA	NDE1_S282 →	-0.813	-0.876	<.001	<.001	3	4
UCEC	RASA3_S809 →	+1.283	+0.968	.005	<.001	3	4
UCEC	ILK_S232 →	+1.384	+1.277	.002	<.001	3	4
UCEC	GNG11 →	+0.881	+1.036	<.001	<.001	3	4
LUAD	AGK →	-0.215	-0.404	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,434 associations by consensus.

SMCO3 vs APCS — UCEC

Explore this scatter interactively →