SMCO3

Across TCGA cell cohorts, SMCO3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,215 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMCO3-associated GO terms across cancer lineages are Protein stabilization, Regulation of cell division, and Protein localization to vacuole. Each is linked with SMCO3 in more than 5 cancer types. Because this analysis shows association rather than direction, both SMCO3-to-partner and partner-to-SMCO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by SMCO3-low versus SMCO3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMCO3→partner) and Y-score (partner→SMCO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein stabilization →	+0.068	+0.125	<.001	.007	3	6
LUNG_NSCLC_LUAD	Regulation of cell division →	+0.043	+0.095	<.001	.003	3	6
KIDNEY	Protein localization to vacuole →	+0.063	+0.103	.001	.005	3	6
BLOOD_Leukemia	RNA catabolic process →	+0.036	+0.052	<.001	.005	3	6
KIDNEY	Error-prone translesion synthesis →	+0.055	+0.099	.001	.006	3	5
OVARY	Spliceosomal complex assembly →	+0.047	+0.110	.007	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,215 associations by consensus.

Protein stabilization by SMCO3 expression — STOMACH

Explore this box plot interactively →