Across TCGA patient cohorts, SMCO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,684 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SMCO1-associated GO terms across cancer lineages are Methylation, Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, and Spliceosomal complex assembly. Each is linked with SMCO1 in more than 16 cancer types. Because this analysis shows association rather than direction, both SMCO1-to-partner and partner-to-SMCO1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMCO1→partner) and Y-score (partner→SMCO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Methylation →	+0.054	+0.185	<.001	<.001	3	16
SCLC	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.081	+0.096	.002	.002	2	17
SCLC	Spliceosomal complex assembly →	+0.125	+0.172	<.001	<.001	2	16
STAD	Negative regulation of DNA-templated transcription, elongation →	+0.114	+0.208	<.001	<.001	2	16
STAD	Regulation of DNA repair →	+0.057	+0.165	<.001	<.001	3	15
STAD	Protein neddylation →	+0.067	+0.167	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,684 associations by consensus.

Exploration

SMCO1 survival (RNA) · tumor vs normal (RNA) · all SMCO1 data types