Across TCGA cell cohorts, SMCO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,502 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SMCO1-associated GO terms across cancer lineages are Positive regulation of extracellular matrix disassembly, mRNA 3'-splice site recognition, and Regulation of post-translational protein modification. Each is linked with SMCO1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SMCO1-to-partner and partner-to-SMCO1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMCO1→partner) and Y-score (partner→SMCO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of extracellular matrix disassembly →	+0.164	+0.075	<.001	.006	3	7
BONE	mRNA 3'-splice site recognition →	+0.072	+0.028	.005	.005	3	7
OVARY	Regulation of post-translational protein modification →	+0.061	+0.032	.001	.002	3	7
OVARY	Regulation of protein modification by small protein conjugation or removal →	+0.066	+0.033	.001	.002	3	6
LUNG_NSCLC_LUAD	Peripheral nervous system myelin maintenance →	+0.110	+0.023	.008	.005	3	6
LUNG_NSCLC_LUAD	Regulation of viral process →	+0.064	+0.028	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,502 associations by consensus.

Exploration

SMCO1 survival (RNA) · tumor vs normal (RNA) · all SMCO1 data types