Across TCGA cell cohorts, SMCO1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SMCO1-associated genes across cancer lineages are FCN2 and C1QTNF7. Each is linked with SMCO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMCO1-to-partner and partner-to-SMCO1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMCO1→partner) and Y-score (partner→SMCO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FCN2 →	+0.039	+4.415	<.001	.007	3	1
LARGE_INTESTINE	C1QTNF7 →	+0.083	+4.108	.007	.008	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

SMCO1 survival (RNA) · tumor vs normal (RNA) · all SMCO1 data types