SMARCE1P4

Across TCGA pan-cancer cohorts, SMARCE1P4 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated SMARCE1P4 data layer.

The strongest signal is observed in thymoma (THYM), where higher SMARCE1P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SMARCE1P4 expression acts as an unfavorable survival marker, although some lineages such as READ and ESCA show a favorable association.

THYM, UCEC, and ACC are the cancer types where SMARCE1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	All	0.661	0.974	<.001	135	view →
UCEC	OS	Tertile	III,IV	0.263	0.613	.003	78	view →
ACC	DFS	Tertile	II,III,IV	0.102	0.647	<.001	66	view →
UVM	DFS	Tertile	All	0.141	0.745	.011	36	view →
LGG	OS	Tertile	All	0.542	0.811	<.001	33	view →
LUSC	OS	Tertile	III,IV	0.054	0.768	<.001	30	view →
LUAD	OS	Tertile	III,IV	0.240	0.667	.023	18	view →
COAD	OS	Tertile	II,III,IV	0.235	0.676	.024	12	view →
STAD	DFS	Quartile	IV	0.087	0.412	.002	9	view →
HNSC	OS	Tertile	III,IV	0.355	0.684	.022	9	view →
READ	OS	Tertile	III,IV	0.772	0.542	.006	6	view →
ESCA	OS	Quartile	II,III,IV	0.841	0.620	.018	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

SMARCE1P4–THYM (OS)

Open the THYM breakdown →