SMARCE1P3

Across TCGA pan-cancer cohorts, SMARCE1P3 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated SMARCE1P3 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher SMARCE1P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SMARCE1P3 expression acts as an unfavorable survival marker, although some lineages such as PRAD and READ show a favorable association.

MESO, LGG, and THYM are the cancer types where SMARCE1P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Quartile	All	0.230	0.429	.001	62	view →
LGG	OS	Tertile	All	0.322	0.509	<.001	39	view →
THYM	OS	Quartile	II,III,IV	0.827	1.000	.008	19	view →
PRAD	DFS	Median	All	0.971	0.914	.002	14	view →
READ	OS	Median	III,IV	0.812	0.473	.011	13	view →
OV	OS	Median	II,III,IV	0.645	0.721	.012	12	view →
STAD	OS	Quartile	III,IV	0.219	0.630	.014	9	view →
LUAD	OS	Tertile	III,IV	0.475	0.756	.006	9	view →
BRCA	DFS	Median	All	0.481	0.554	.025	6	view →
ESCA	DFS	Median	All	0.454	0.604	.010	6	view →
SKCM	DFS	Quartile	II,III,IV	0.134	0.240	.020	4	view →
HNSC	DFS	Quartile	All	0.517	0.318	.043	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

SMARCE1P3–MESO (DFS)

Open the MESO breakdown →