Across TCGA pan-cancer cohorts, SMARCE1P1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SMARCE1P1’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SMARCE1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SMARCE1P1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.
HNSC, STAD, and COAD are the cancer types where SMARCE1P1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SMARCE1P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.