SMARCD2

Across TCGA cell cohorts, SMARCD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,964 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SMARCD2-associated GO terms across cancer lineages are Response to sorbitol, Positive regulation of hematopoietic stem cell proliferation, and Cap-dependent translational initiation. Each is linked with SMARCD2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SMARCD2-to-partner and partner-to-SMARCD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to sorbitol grouped by SMARCD2-low versus SMARCD2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCD2→partner) and Y-score (partner→SMARCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Response to sorbitol →	+0.185	+0.960	<.001	.001	3	10
BREAST	Positive regulation of hematopoietic stem cell proliferation →	+0.127	+0.947	<.001	.002	3	10
OVARY	Cap-dependent translational initiation →	+0.092	+0.650	<.001	<.001	3	10
BONE	Protein-DNA complex disassembly →	+0.145	+0.791	.001	<.001	3	10
BONE	Nucleosome disassembly →	+0.210	+0.886	<.001	<.001	3	10
PANCREAS	DNA strand elongation involved in DNA replication →	+0.129	+0.530	.001	.003	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,964 associations by consensus.

Response to sorbitol by SMARCD2 expression — PANCREAS

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