SMARCD1

Across TCGA patient cohorts, SMARCD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,670 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMARCD1-associated proteins across cancer lineages are WDR5, XPO1, and SF3B3. Each is linked with SMARCD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SMARCD1-to-partner and partner-to-SMARCD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCD1 versus WDR5 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCD1→partner) and Y-score (partner→SMARCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR5 →	+0.231	+0.417	<.001	<.001	3	7
LSCC	XPO1 →	+0.286	+0.545	<.001	<.001	3	6
GBM	SF3B3 →	+0.260	+0.511	<.001	<.001	3	6
LSCC	SMARCA5 →	+0.269	+0.456	<.001	<.001	3	6
GBM	SNRPD2 →	+0.279	+0.476	<.001	<.001	3	6
GBM	DDX23 →	+0.298	+0.481	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,670 associations by consensus.

SMARCD1 vs WDR5 — LSCC

Explore this scatter interactively →