SMARCD1

Across TCGA cell cohorts, SMARCD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,879 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMARCD1-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, Regulation of DNA recombination, and Epigenetic regulation of gene expression. Each is linked with SMARCD1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SMARCD1-to-partner and partner-to-SMARCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by SMARCD1-low versus SMARCD1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCD1→partner) and Y-score (partner→SMARCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation involved in DNA replication →	+0.164	+1.071	.002	.001	3	18
SOFT_TISSUE	Regulation of DNA recombination →	+0.088	+0.944	<.001	.002	3	17
STOMACH	Epigenetic regulation of gene expression →	+0.075	+0.977	<.001	.001	3	17
LUNG_SCLC	Host-mediated perturbation of viral transcription →	+0.119	+0.720	<.001	<.001	3	17
SOFT_TISSUE	Regulation of double-strand break repair via homologous recombination →	+0.098	+0.886	.001	.003	3	17
OESOPHAGUS	Regulation of nucleotide-excision repair →	+0.146	+1.255	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,879 associations by consensus.

DNA strand elongation involved in DNA replication by SMARCD1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →