SMARCC2

Across TCGA patient cohorts, SMARCC2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,028 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMARCC2-associated genes across cancer lineages are PAN2, RIC8B, and ING4. Each is linked with SMARCC2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SMARCC2-to-partner and partner-to-SMARCC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCC2 versus PAN2 in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCC2→partner) and Y-score (partner→SMARCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PAN2 →	+0.779	+0.308	<.001	<.001	3	8
LSCC	RIC8B →	+0.450	+0.190	<.001	<.001	3	8
BRCA	ING4 →	+0.588	+0.208	<.001	<.001	3	7
LUAD	ZC3H10 →	+0.387	+0.210	<.001	<.001	3	7
HNSC	KANSL2 →	+0.661	+0.165	.004	.003	3	7
BRCA	ZNF740 →	+0.553	+0.202	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,028 associations by consensus.

SMARCC2 vs PAN2 — BRCA

Explore this scatter interactively →