SMARCC1

Across TCGA patient cohorts, SMARCC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,074 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMARCC1-associated proteins across cancer lineages are TOP2B, RBM12, and SF3B3. Each is linked with SMARCC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SMARCC1-to-partner and partner-to-SMARCC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCC1 versus TOP2B in GBM, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCC1→partner) and Y-score (partner→SMARCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TOP2B →	+0.483	+0.568	<.001	<.001	3	8
GBM	RBM12 →	+0.296	+0.431	<.001	<.001	3	7
LSCC	SF3B3 →	+0.217	+0.546	<.001	<.001	3	7
GBM	QRICH1 →	+0.260	+0.505	<.001	<.001	3	6
GBM	GATAD2B →	+0.368	+0.537	<.001	<.001	3	6
HNSC	HDAC2 →	+0.438	+0.708	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,074 associations by consensus.

SMARCC1 vs TOP2B — GBM

Explore this scatter interactively →