SMARCC1

Across TCGA cell cohorts, SMARCC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,593 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SMARCC1-associated GO terms across cancer lineages are Protein-DNA complex disassembly, Nucleosome disassembly, and Epigenetic regulation of gene expression. Each is linked with SMARCC1 in more than 19 cancer types. Because this analysis shows association rather than direction, both SMARCC1-to-partner and partner-to-SMARCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex disassembly grouped by SMARCC1-low versus SMARCC1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCC1→partner) and Y-score (partner→SMARCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Protein-DNA complex disassembly →	+0.175	+1.447	<.001	<.001	3	20
KIDNEY	Nucleosome disassembly →	+0.202	+1.558	<.001	<.001	3	20
BONE	Epigenetic regulation of gene expression →	+0.071	+1.000	<.001	.005	3	18
KIDNEY	Mitotic spindle assembly →	+0.094	+1.111	<.001	<.001	3	18
BONE	Regulation of double-strand break repair via homologous recombination →	+0.129	+1.514	<.001	<.001	3	18
SOFT_TISSUE	DNA-templated transcription elongation →	+0.107	+1.178	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,593 associations by consensus.

Protein-DNA complex disassembly by SMARCC1 expression — KIDNEY

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