SMARCC1

Across TCGA cell cohorts, SMARCC1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,602 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SMARCC1-associated genes across cancer lineages are SMARCAD1, CAPN2, and DUSP5. Each is linked with SMARCC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMARCC1-to-partner and partner-to-SMARCC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCC1 versus SMARCAD1 in URINARY_TRACT, with a Pearson correlation of 0.95.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCC1→partner) and Y-score (partner→SMARCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	SMARCAD1 →	+0.532	+1.058	.008	.006	3	5
OVARY	CAPN2 →	-1.668	-1.347	<.001	<.001	3	5
BREAST	DUSP5 →	-1.441	-0.837	.001	.001	3	5
BLOOD_Leukemia	ORMDL3 →	+1.179	+1.091	.006	.002	3	4
LARGE_INTESTINE	ZSCAN30 →	+1.305	+0.656	.001	.006	3	4
OVARY	KLHDC3 →	+1.043	+1.159	.005	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,602 associations by consensus.

SMARCC1 vs SMARCAD1 — URINARY_TRACT

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